Blast injury research models

Blast injury research models.

Blast injuries are an increasing problem in both military and civilian practice. Primary blast injury to the lungs (blast lung) is found in a clinically significant proportion of casualties from explosions even in an open environment, and in a high proportion of severely injured casualties following explosions in confined spaces. Blast casualties also commonly suffer secondary and tertiary blas...

Blast Brain Injury: Quantifying Axonal Injury Due to Primary Blast

This review includes a study of the cause of Necrotizing Fasciitis (NF) by Group A Streptococci (GAS), the existing treatment of the infection, and the proposal of a novel therapy. The purpose of this review is to determine the microbiology and pathogenesis of NF in addition to how the treatment may be modified to best target the infecting pathogens. Existing treatments include rapid surgical d...

Updates to Blast Injury Criteria Models for Nuclear Casualty Estimation

Biomechanical analysis of blast-induced traumatic brain injury

  Purpose: Blast-induced traumatic brain injury (bTBI) is one of the causes of death or permanent   invalidity which can occur unexpectedly in both military and civilian populations. This study   set out to conduct a combined Eulerian-Lagrangian computational analysis of the interaction   between a single planar blast wave and a human head in order to assess the extent of intracranial   shock w...

A Multiscale Approach to Blast Neurotrauma Modeling: Part II: Methodology for Inducing Blast Injury to in vitro Models

Due to the prominent role of improvised explosive devices (IEDs) in wounding patterns of U.S. war-fighters in Iraq and Afghanistan, blast injury has risen to a new level of importance and is recognized to be a major cause of injuries to the brain. However, an injury risk-function for microscopic, macroscopic, behavioral, and neurological deficits has yet to be defined. While operational blast i...